| Gene Information | |
|---|---|
| Gene Name | ZTNFR9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O14763 |
| Gene Card | TNFRSF10B |
| Uniprot ID | O14763 |
| Pfam | PF00531; PF00020 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1D0G (X-ray 2.40A ) 1D4V (X-ray 2.20A ) 1DU3 (X-ray 2.20A ) 1ZA3 (X-ray 3.35A ) 2H9G (X-ray 2.32A ) 3X3F (X-ray 2.10A ) 4I9X (X-ray 2.10A ) 4N90 (X-ray 3.30A ) 4OD2 (X-ray 3.20A ) 6NHW (NMR - ) 6NHY (NMR - ) 6T3J (X-ray 3.05A ) |
| DBSNP | rs1129424 rs1047266 rs13265018 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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