| Gene Information | |
|---|---|
| Gene Name | CCKAR |
| Organism | Homo sapiens (Human) |
| Gene Length | 428 |
| Protein Names | Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR) (Cholecystokinin-1 receptor) (CCK1-R) |
| Target Name | cholecystokinin receptor type a |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000163394 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P32238 |
| Gene Card | CCKAR |
| Uniprot ID | P32238 |
| Pfam | PF00001; PF09193 |
| In ASD | yes |
| Allosteric Prediction | yes (1.086271996) |
| Ortholog in Animals | Alpaca_ CCKAR ( ortholog_one2one ) Dog_ CCKAR ( ortholog_one2one ) GuineaPig_ CCKAR ( ortholog_one2one ) Macaque_ CCKAR ( ortholog_one2one ) Mouse_ Cckar ( ortholog_one2one ) Pig_ CCKAR ( ortholog_one2one ) Rat_ Cckar ( ortholog_one2one ) Rabbit_ CCKAR ( ortholog_one2one ) |
| Ohnologs | CCKBR |
| Paralogs | CCKBR, NPFFR1, HCRTR2, HCRTR1, NPFFR2, OXTR, AVPR2, AVPR1B, AVPR1A, GNRHR, GALR3, GPR22, GPR150, FFAR4, GALR1, QRFPR |
| Tissue | gall.bladder, stomach |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1D6G (NMR - ) 1HZN (NMR - ) 7EZH (EM 3.20A ) 7EZK (EM 3.10A ) 7EZM (EM 2.90A ) 7F8U (X-ray 2.80A ) 7F8X (X-ray 3.00A ) 7F8Y (X-ray 2.50A ) 7MBX (EM 1.95A ) 7MBY (EM 2.44A ) 7XOU (EM 3.20A ) 7XOV (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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