| Gene Information | |
|---|---|
| Gene Name | MAGEA10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000124260 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P43363 |
| Gene Card | MAGEA10 |
| Uniprot ID | P43363 |
| Pfam | PF01454; PF12440 |
| In ASD | no |
| Allosteric Prediction | no (-1.254335033) |
| Ortholog in Animals | Alpaca_ MAGEA10 ( ortholog_one2many ) Macaque_ MAGEA10 ( ortholog_one2one ) Mouse_ Magea14 ( ortholog_one2many ) Mouse_ Magea8 ( ortholog_one2many ) Mouse_ Magea9 ( ortholog_one2many ) Mouse_ Magea3 ( ortholog_one2many ) Mouse_ Magea10 ( ortholog_one2many ) Mouse_ Magea2 ( ortholog_one2many ) Mouse_ Magea6 ( ortholog_one2many ) Mouse_ Magea5 ( ortholog_one2many ) Mouse_ Magea1 ( ortholog_one2many ) Mouse_ Magea4 ( ortholog_one2many ) Pig_ MAGEA10 ( ortholog_one2one ) Rat_ Magea10 ( ortholog_one2many ) Rat_ RGD1559726 ( ortholog_one2many ) Rat_ Magea4 ( ortholog_one2many ) Rat_ Magea9 ( ortholog_one2many ) Rat_ MGC114492 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2 |
| Tissue | placenta |
| Tissue Specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for spermatogonia, spermatocytes and placenta. {ECO:0000269|PubMed:21710496}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PBC (X-ray 2.04A ) 7PDW (X-ray 1.82A ) 7QPJ (X-ray 1.54A ) |
| DBSNP | rs210585 rs210586 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21710496}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |