| Gene Information | |
|---|---|
| Gene Name | PHB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 272 |
| Protein Names | Prohibitin 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000167085 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P35232 |
| Gene Card | PHB1 |
| Uniprot ID | P35232 |
| Pfam | PF01145 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | Alpaca_ PHB1 ( ortholog_one2one ) GuineaPig_ PHB1 ( ortholog_one2one ) Macaque_ PHB1 ( ortholog_one2one ) Mouse_ Phb ( ortholog_one2one ) Pig_ PHB1 ( ortholog_one2one ) Rat_ AABR07037878.1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PHB2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in different tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121918373 rs121918372 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:14500729, ECO:0000269|PubMed:20959514}. Nucleus {ECO:0000269|PubMed:14500729, ECO:0000269|PubMed:20959514, ECO:0000269|PubMed:31899195}. Cytoplasm {ECO:0000269|PubMed:14500729, ECO:0000269|PubMed:31899195}. Cell membrane {ECO:0000269|PubMed:22997079, ECO:0000269|PubMed:24003225}. |
| Mouse PG classification | NA |
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