| Gene Information | |
|---|---|
| Gene Name | ZP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | Zona pellucida sperm-binding protein 3 (Sperm receptor) (ZP3A/ZP3B) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000188372 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P21754 |
| Gene Card | ZP3 |
| Uniprot ID | P21754 |
| Pfam | PF00100 |
| In ASD | no |
| Allosteric Prediction | no (-0.290583125) |
| Ortholog in Animals | Alpaca_ ZP3 ( ortholog_one2many ) Dog_ ZP3 ( ortholog_one2many ) Macaque_ ZP3 ( ortholog_one2many ) Mouse_ Zp3 ( ortholog_one2many ) Pig_ ZP3 ( ortholog_one2many ) Rat_ Zp3 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | POMZP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in oocytes (at protein level). {ECO:0000269|PubMed:29895852}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2286428 rs1554625334 rs2906999 rs2906997 |
| Subcellular location [CC] | [Processed zona pellucida sperm-binding protein 3]: Zona pellucida {ECO:0000269|PubMed:29895852}.; Cell membrane {ECO:0000250|UniProtKB:P48833}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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