| Gene Information | |
|---|---|
| Gene Name | ZNT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Proton-coupled zinc antiporter SLC30A2 (Solute carrier family 30 member 2) (Zinc transporter 2) (ZnT-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BRI3 |
| Gene Card | SLC30A2 |
| Uniprot ID | Q9BRI3 |
| Pfam | PF01545 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587776926 rs185398527 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:19496757}; Multi-pass membrane protein {ECO:0000255}. Zymogen granule membrane {ECO:0000250|UniProtKB:Q2HJ10}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:19496757, ECO:0000269|PubMed:25808614}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:25808614, ECO:0000269|PubMed:30893306}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000269|PubMed:21289295}; Multi-pass membrane protein {ECO:0000255}. Note=Localization to lysosomes is induced by TNF-alpha. {ECO:0000269|PubMed:25808614}.; [Isoform 2]: Cell membrane {ECO:0000269|PubMed:19496757}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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