| Gene Information | |
|---|---|
| Gene Name | ZNRF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 429 |
| Protein Names | E3 ubiquitin-protein ligase ZNRF4 (EC 2.3.2.27) (Nixin) (RING finger protein 204) (RING-type E3 ubiquitin transferase ZNRF4) (Zinc/RING finger protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000105428 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WWF5 |
| Gene Card | ZNRF4 |
| Uniprot ID | Q8WWF5 |
| Pfam | PF02225; PF13639 |
| In ASD | no |
| Allosteric Prediction | no (-1.156865927) |
| Ortholog in Animals | Macaque_ ZNRF4 ( ortholog_one2one ) Mouse_ Znrf4 ( ortholog_one2one ) Pig_ ZNRF4 ( ortholog_one2one ) Rat_ Znrf4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNF133, RNF149, RNF130, RNF150, RNF215, RNF128, RNF167, RNF13, RNF148 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2240743 rs2240744 rs2240745 rs8103406 rs8107825 rs8104246 rs17304380 rs16992985 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21205830, ECO:0000269|PubMed:24387786, ECO:0000269|PubMed:28656966}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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