| Gene Information | |
|---|---|
| Gene Name | PRKCB |
| Organism | Homo sapiens (Human) |
| Gene Length | 671 |
| Protein Names | Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13) |
| Target Name | protein kinase c beta type |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000166501 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P05771 |
| Gene Card | PRKCB |
| Uniprot ID | P05771 |
| Pfam | PF00130; PF00168; PF00069; PF00433 |
| In ASD | yes |
| Allosteric Prediction | yes (2.081679935) |
| Ortholog in Animals | Alpaca_ PRKCB ( ortholog_one2one ) Dog_ PRKCB ( ortholog_one2one ) GuineaPig_ PRKCB ( ortholog_one2one ) Macaque_ PRKCB ( ortholog_one2one ) Mouse_ Prkcb ( ortholog_one2one ) Pig_ PRKCB ( ortholog_one2one ) Rat_ Prkcb ( ortholog_one2one ) Rabbit_ PRKCB ( ortholog_one2one ) |
| Ohnologs | PRKCG, PRKCA |
| Paralogs | PKN3, PKN1, PRKCE, PRKCH, PRKCZ, PRKCI, PKN2, PRKCG, PRKCA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I0E (X-ray 2.60A ) |
| DBSNP | rs764534677 rs1466858740 rs35631544 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20228790}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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