| Gene Information | |
|---|---|
| Gene Name | ZNFN3A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 428 |
| Protein Names | Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H7B4 |
| Gene Card | SMYD3 |
| Uniprot ID | Q9H7B4 |
| Pfam | PF00856; PF01753 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas. {ECO:0000269|PubMed:15235609}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MEK (X-ray 2.10A ) 3OXF (X-ray 2.82A ) 3OXG (X-ray 3.41A ) 3OXL (X-ray 3.60A ) 3PDN (X-ray 1.70A ) 3QWP (X-ray 1.53A ) 3RU0 (X-ray 1.85A ) 5CCL (X-ray 1.50A ) 5CCM (X-ray 2.30A ) 5EX0 (X-ray 2.70A ) 5EX3 (X-ray 2.41A ) 5HI7 (X-ray 2.15A ) 5HQ8 (X-ray 1.72A ) 5V37 (X-ray 1.42A ) 5XXD (X-ray 2.31A ) 5XXG (X-ray 2.14A ) 5XXJ (X-ray 1.69A ) 5YJO (X-ray 2.13A ) 6IJL (X-ray 2.35A ) 6O9O (X-ray 1.59A ) 6P6G (X-ray 1.59A ) 6P6K (X-ray 1.55A ) 6P7Z (X-ray 1.19A ) 6PAF (X-ray 1.24A ) 6YUH (X-ray 1.93A ) 6ZRB (X-ray 1.55A ) 7BJ1 (X-ray 1.61A ) 7O2A (X-ray 1.57A ) 7O2B (X-ray 2.03A ) 7O2C (X-ray 1.52A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15235609}. Nucleus {ECO:0000269|PubMed:15235609, ECO:0000269|PubMed:25738358}. Note=Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M. {ECO:0000269|PubMed:15235609}. |
| Mouse PG classification | NA |
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