| Gene Information | |
|---|---|
| Gene Name | CADM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 442 |
| Protein Names | Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000182985 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BY67 |
| Gene Card | CADM1 |
| Uniprot ID | Q9BY67 |
| Pfam | PF08205; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.148974823) |
| Ortholog in Animals | Alpaca_ CADM1 ( ortholog_one2one ) Dog_ CADM1 ( ortholog_one2one ) GuineaPig_ CADM1 ( ortholog_one2one ) Macaque_ CADM1 ( ortholog_one2one ) Mouse_ Cadm1 ( ortholog_one2one ) Pig_ CADM1 ( ortholog_one2one ) Rat_ Cadm1 ( ortholog_one2one ) Rabbit_ CADM1 ( ortholog_one2one ) |
| Ohnologs | CADM4 |
| Paralogs | TIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, CADM4, SMAGP, CD226, PVR |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BIN (X-ray 2.30A ) 4H5S (X-ray 1.70A ) |
| DBSNP | rs45525440 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11279526, ECO:0000269|PubMed:22438059}; Single-pass type I membrane protein {ECO:0000269|PubMed:11279526}. Synapse {ECO:0000250|UniProtKB:Q8R5M8}. Note=Localized to the basolateral plasma membrane of epithelial cells in gall bladder. {ECO:0000250|UniProtKB:Q8R5M8}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |