| Gene Information | |
|---|---|
| Gene Name | TAS2R40 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Taste receptor type 2 member 40 (T2R40) (G-protein coupled receptor 60) (Taste receptor type 2 member 58) (T2R58) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000221937 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P59535 |
| Gene Card | TAS2R40 |
| Uniprot ID | P59535 |
| Pfam | PF05296 |
| In ASD | no |
| Allosteric Prediction | yes (0.682006078) |
| Ortholog in Animals | Alpaca_ TAS2R40 ( ortholog_one2many ) Dog_ TAS2R40 ( ortholog_one2one ) GuineaPig_ TAS2R40 ( ortholog_one2one ) Macaque_ TAS2R40 ( ortholog_one2one ) Mouse_ Tas2r144 ( ortholog_one2one ) Pig_ TAS2R40 ( ortholog_one2one ) Rat_ Tas2r144 ( ortholog_one2one ) Rabbit_ TAS2R40 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TAS2R39, TAS2R20, TAS2R50, TAS2R4, TAS2R43, TAS2R14, TAS2R9, TAS2R19, TAS2R3, TAS2R41, TAS2R5, TAS2R38, TAS2R30, TAS2R46, TAS2R13, TAS2R8, TAS2R7, TAS2R60, TAS2R1, TAS2R31, TAS2R10, TAS2R16, TAS2R42 |
| Tissue | NA |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17164164 rs10260248 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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