| Gene Information | |
|---|---|
| Gene Name | ZNF22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | Zinc finger protein 22 (Zinc finger protein KOX15) (Zinc finger protein Krox-26) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000165512 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P17026 |
| Gene Card | ZNF22 |
| Uniprot ID | P17026 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.772553633) |
| Ortholog in Animals | Alpaca_ ZNF22 ( ortholog_one2one ) Dog_ ZNF22 ( ortholog_one2one ) Macaque_ ZNF22 ( ortholog_one2one ) Mouse_ Zfp422 ( ortholog_one2one ) Pig_ ZNF22 ( ortholog_one2one ) Rat_ Zfp422 ( ortholog_one2one ) Rabbit_ ZNF22 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZFP41, ZNF92, ZNF730, ZNF680, ZNF479, ZNF431, ZNF737, ZNF66, ZNF98, ZNF257, ZNF253, ZNF273, ZNF100, ZNF723, ZNF675, ZNF626, ZNF430, ZNF114 |
| Tissue | NA |
| Tissue Specificity | In the embryo, expressed in developing craniofacial structures including dental epithelium of maxillary molar tooth organs, tongue epithelium and muscle, and craniofacial bone osteoblasts. In the adult, expressed in mesoderm-derived tissues such as skeletal muscle, heart, kidney and liver. Intermediate expression in spleen, thymus and brain. Low levels in endoderm-derived tissues such as intestine and colon. {ECO:0000269|PubMed:14630903}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3740093 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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