| Gene Information | |
|---|---|
| Gene Name | M6A |
| Organism | Homo sapiens (Human) |
| Gene Length | 278 |
| Protein Names | Neuronal membrane glycoprotein M6-a (M6a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P51674 |
| Gene Card | GPM6A |
| Uniprot ID | P51674 |
| Pfam | PF01275 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1049820 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P35802}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P35802}. Cell projection, axon {ECO:0000250|UniProtKB:P35802}. Cell projection, growth cone {ECO:0000250|UniProtKB:P35802}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q812E9}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q812E9}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q812E9}. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons (By similarity). Localized to the growth cone edge membrane of elongating axons (By similarity). {ECO:0000250|UniProtKB:P35802, ECO:0000250|UniProtKB:Q812E9}. |
| Mouse PG classification | NA |
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