Gene Information
Gene NameRNF185
OrganismHomo sapiens (Human)
Gene Length192
Protein NamesE3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000138942 )
Evolutionary StageEukaryota
AlphaFoldDBQ96GF1
Gene CardRNF185
Uniprot IDQ96GF1
PfamNA
In ASDno
Allosteric Predictionno (-0.980874643)
Ortholog in AnimalsAlpaca_ RNF185 ( ortholog_one2one )
GuineaPig_ RNF185 ( ortholog_one2one )
Mouse_ Rnf185 ( ortholog_one2one )
Pig_ RNF185 ( ortholog_one2one )
Rat_ Rnf185 ( ortholog_one2one )
Rabbit_ RNF185 ( ortholog_one2one )
OhnologsRNF5
ParalogsRNF5
TissueNA
Tissue SpecificityUbiquitously expressed. {ECO:0000269|PubMed:27485036}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion outer membrane {ECO:0000269|PubMed:21931693};
Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24019521, ECO:0000269|PubMed:27485036};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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