| Gene Information | |
|---|---|
| Gene Name | ACY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 408 |
| Protein Names | Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) |
| Target Name | aminoacylase-1 |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000243989 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q03154 |
| Gene Card | ACY1 |
| Uniprot ID | Q03154 |
| Pfam | PF07687; PF01546 |
| In ASD | no |
| Allosteric Prediction | yes (0.274865302) |
| Ortholog in Animals | Alpaca_ ACY1 ( ortholog_one2one ) Dog_ ACY1 ( ortholog_one2one ) GuineaPig_ ACY1 ( ortholog_one2one ) Macaque_ ACY1 ( ortholog_one2one ) Mouse_ Acy1 ( ortholog_one2one ) Pig_ ACY1 ( ortholog_one2one ) Rat_ Acy1 ( ortholog_one2one ) Rabbit_ ACY1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PM20D1, CNDP1, CNDP2 |
| Tissue | duodenum, kidney, small.intestine, liver |
| Tissue Specificity | Expression is highest in kidney, strong in brain and weaker in placenta and spleen. {ECO:0000269|PubMed:16465618}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Q7L (X-ray 1.40A ) |
| DBSNP | rs887540 rs121912700 rs121912699 rs121912698 rs150480963 rs148346337 rs2229152 rs121912701 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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