| Gene Information | |
|---|---|
| Gene Name | DYNLT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 113 |
| Protein Names | Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000146425 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P63172 |
| Gene Card | DYNLT1 |
| Uniprot ID | P63172 |
| Pfam | PF03645 |
| In ASD | no |
| Allosteric Prediction | no (-0.969153264) |
| Ortholog in Animals | Alpaca_ DYNLT1 ( ortholog_one2one ) Alpaca_ DYNLT1 ( ortholog_one2many ) Dog_ DYNLT1 ( ortholog_one2one ) GuineaPig_ DYNLT1 ( ortholog_one2one ) Macaque_ DYNLT1 ( ortholog_one2one ) Mouse_ Dynlt1f ( ortholog_one2many ) Mouse_ Dynlt1a ( ortholog_one2many ) Mouse_ Dynlt1c ( ortholog_one2many ) Mouse_ Dynlt1b ( ortholog_one2many ) Pig_ DYNLT1 ( ortholog_one2one ) Rat_ Dynlt1 ( ortholog_one2one ) Rabbit_ DYNLT1 ( ortholog_one2one ) |
| Ohnologs | DYNLT3 |
| Paralogs | DYNLT4, DYNLT5, DYNLT2, DYNLT3, DYNLT2B |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level). {ECO:0000269|PubMed:14583445}. |
| Pharmacological Animal Models | 0.110243(Chimpanzee);0.061719(Mouse);NULL(Rat);0.030000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5JPW (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes to mitotic spindles. {ECO:0000250}. |
| Mouse PG classification | NA |
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