Gene Information
Gene NameZNF589
OrganismHomo sapiens (Human)
Gene Length364
Protein NamesZinc finger protein 589 (Stem cell zinc finger protein 1)
Target NameNA
Target TypeNA
Gene Age70 ( ENSG00000164048 )
Evolutionary StageMammalia
AlphaFoldDBQ86UQ0
Gene CardZNF589
Uniprot IDQ86UQ0
PfamPF01352; PF00096
In ASDno
Allosteric Predictionno (-0.161734376)
Ortholog in AnimalsAlpaca_ ZNF589 ( ortholog_one2one )
Macaque_ ZNF589 ( ortholog_one2one )
OhnologsNA
ParalogsZNF875, ZNF556, ZNF248, ZFP90, ZFP69, ZNF891, ZNF20, ZNF487, ZNF778, ZNF614, ZNF491, ZNF440, ZNF69, ZNF763, ZNF439, PRDM9, ZNF582, ZNF684, ZNF35, ZNF558, ZNF557, ZNF619, ZNF596, ZNF343, ZFP37, ZNF180, ZNF80, ZNF749, ZNF550, ZNF124, ZNF169, ZNF404, ZNF329, ZNF133, ZNF554, ZNF705A, ZNF705D, ZNF705B, ZNF705G, ZNF19, ZNF560, ZNF264, ZNF599, ZNF805, ZNF555, ZNF266, ZNF566, ZNF620, ZNF425, ZNF337, ZFP69B, ZNF10, ZNF177, ZNF77, ZNF674, KRBOX4, ZNF669, ZNF846, ZNF529, ZNF25, ZNF70, ZNF559
TissueNA
Tissue SpecificityIsoform 2 is widely expressed. Isoform 3 is only expressed in CD34(+) cells. {ECO:0000269|PubMed:10029171}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs9847953  rs11718329 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:23665872}.
Mouse PG classificationNA
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