| Gene Information | |
|---|---|
| Gene Name | HMOX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 316 |
| Protein Names | Heme oxygenase 2 (HO-2) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 2 soluble form] |
| Target Name | heme oxygenase 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000103415 ) 3 ( ENSG00000277424 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P30519 |
| Gene Card | HMOX2 |
| Uniprot ID | P30519 |
| Pfam | PF01126 |
| In ASD | no |
| Allosteric Prediction | yes (0.913733723) |
| Ortholog in Animals | Alpaca_ HMOX2 ( ortholog_one2one ) Dog_ HMOX2 ( ortholog_one2one ) GuineaPig_ HMOX2 ( ortholog_one2one ) Macaque_ HMOX2 ( ortholog_one2one ) Mouse_ Hmox2 ( ortholog_one2one ) Pig_ HMOX2 ( ortholog_one2one ) Rat_ Hmox2 ( ortholog_one2one ) Rabbit_ HMOX2 ( ortholog_one2one ) |
| Ohnologs | HMOX1 |
| Paralogs | HMOX1 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Q32 (X-ray 2.40A ) 2QPP (X-ray 2.61A ) 2RGZ (X-ray 2.61A ) 4WMH (X-ray 2.50A ) 5UC8 (X-ray 2.00A ) 5UC9 (X-ray 1.90A ) 5UCA (X-ray 2.12A ) |
| DBSNP | rs17884623 rs17880805 |
| Subcellular location [CC] | Microsome membrane {ECO:0000305|PubMed:7890772}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P09601}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}. |
| Mouse PG classification | NA |
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