| Gene Information | |
|---|---|
| Gene Name | RAET1G |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | UL-16 binding protein 5 (Retinoic acid early transcript 1G protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000203722 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6H3X3 |
| Gene Card | RAET1G |
| Uniprot ID | Q6H3X3 |
| Pfam | PF00129 |
| In ASD | no |
| Allosteric Prediction | no (-1.032500872) |
| Ortholog in Animals | Alpaca_ RAET1G ( ortholog_one2one ) Mouse_ Raet1d ( ortholog_many2many ) Mouse_ Raet1e ( ortholog_many2many ) Rat_ Raet1l ( ortholog_many2many ) Rat_ Rrlt ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | HLA-B, HLA-E, HLA-A, HLA-F, HLA-G, HLA-C, MR1, AZGP1, MICA, HFE, MICB, ULBP2, RAET1L, ULBP3, ULBP1, RAET1E, FCGRT, CD1B, CD1A, CD1D, CD1C, CD1E |
| Tissue | adrenal.gland, esophagus, tongue |
| Tissue Specificity | Isoform 1 is highly expressed in colon and in a number of tumor cell lines and highly restricted in normal tissues. Both isoforms are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers. {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:19658097}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9397449 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:20304922}. Endoplasmic reticulum {ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}. Note=Mainly found intracellularly. {ECO:0000269|PubMed:15240696, ECO:0000269|PubMed:19223974, ECO:0000269|PubMed:20304922}.; [Isoform 2]: Secreted {ECO:0000269|PubMed:19223974}. |
| Mouse PG classification | NA |
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