| Gene Information | |
|---|---|
| Gene Name | SLC27A5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 690 |
| Protein Names | Long-chain fatty acid transport protein 5 (FATP-5) (Fatty acid transport protein 5) (Bile acid-CoA ligase) (BA-CoA ligase) (BAL) (Bile acyl-CoA synthetase) (BACS) (EC 6.2.1.7) (Cholate--CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 3) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 5) (Very long-chain acyl-CoA synthetase homolog 2) (VLCS-H2) (VLCSH2) (EC 6.2.1.-) (Very long-chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000083807 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9Y2P5 |
| Gene Card | SLC27A5 |
| Uniprot ID | Q9Y2P5 |
| Pfam | PF00501; PF13193 |
| In ASD | no |
| Allosteric Prediction | no (-0.594380788) |
| Ortholog in Animals | Alpaca_ SLC27A5 ( ortholog_one2one ) Dog_ ZBTB45 ( ortholog_one2one ) GuineaPig_ SLC27A5 ( ortholog_one2one ) Macaque_ SLC27A5 ( ortholog_one2one ) Mouse_ Slc27a5 ( ortholog_one2one ) Pig_ SLC27A5 ( ortholog_one2one ) Rat_ Slc27a5 ( ortholog_one2one ) Rabbit_ SLC27A5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC27A4, ACSBG1, ACSL1, ACSL3, SLC27A3, ACSL6, ACSBG2, SLC27A6, ACSL4, ACSL5, SLC27A2, SLC27A1 |
| Tissue | liver, brain |
| Tissue Specificity | Predominantly expressed in liver. {ECO:0000269|PubMed:10479480}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35350976 rs34415062 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10479480}; Multi-pass membrane protein {ECO:0000255}. Microsome {ECO:0000250|UniProtKB:Q9ES38}. Cell membrane {ECO:0000250|UniProtKB:Q4LDG0}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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