| Gene Information | |
|---|---|
| Gene Name | ST8SIA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 356 |
| Protein Names | Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.3.8) (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialyltransferase St8Sia I) (ST8SiaI) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000111728 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92185 |
| Gene Card | ST8SIA1 |
| Uniprot ID | Q92185 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-1.196529166) |
| Ortholog in Animals | Alpaca_ ST8SIA1 ( ortholog_one2one ) Dog_ ST8SIA1 ( ortholog_one2one ) GuineaPig_ ST8SIA1 ( ortholog_one2one ) Macaque_ ST8SIA1 ( ortholog_one2one ) Mouse_ St8sia1 ( ortholog_one2one ) Pig_ ST8SIA1 ( ortholog_one2one ) Rat_ St8sia1 ( ortholog_one2one ) Rabbit_ ST8SIA1 ( ortholog_one2one ) |
| Ohnologs | ST8SIA6 |
| Paralogs | ST8SIA5, ST8SIA6, ST8SIA2, ST8SIA3, ST8SIA4 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8631981}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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