| Gene Information | |
|---|---|
| Gene Name | SNTG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 539 |
| Protein Names | Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000172554 ) 3 ( ENSG00000281020 ) 3 ( ENSG00000281486 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NY99 |
| Gene Card | SNTG2 |
| Uniprot ID | Q9NY99 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.557561692) |
| Ortholog in Animals | Alpaca_ SNTG2 ( ortholog_one2one ) Dog_ SNTG2 ( ortholog_one2one ) Macaque_ SNTG2 ( ortholog_one2one ) Mouse_ Sntg2 ( ortholog_one2one ) Rat_ Sntg2 ( ortholog_one2one ) |
| Ohnologs | SNTG1 |
| Paralogs | SNTG1, SNTB1, SNTA1, SNTB2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. {ECO:0000269|PubMed:10747910}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7QQL (X-ray 2.44A ) |
| DBSNP | rs28505970 rs6751090 rs13023962 |
| Subcellular location [CC] | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane. |
| Mouse PG classification | NA |
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