| Gene Information | |
|---|---|
| Gene Name | WNT2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 391 |
| Protein Names | Protein Wnt-2b (Protein Wnt-13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000134245 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q93097 |
| Gene Card | WNT2B |
| Uniprot ID | Q93097 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-1.033302912) |
| Ortholog in Animals | Alpaca_ WNT2B ( ortholog_one2one ) Dog_ WNT2B ( ortholog_one2one ) GuineaPig_ WNT2B ( ortholog_one2one ) Macaque_ WNT2B ( ortholog_one2one ) Mouse_ Wnt2b ( ortholog_one2one ) Pig_ WNT2B ( ortholog_one2one ) Rat_ Wnt2b ( ortholog_one2one ) Rabbit_ WNT2B ( ortholog_one2one ) |
| Ohnologs | WNT2, WNT5B, WNT5A, WNT4, WNT7B |
| Paralogs | WNT5A, WNT6, WNT3, WNT4, WNT2, WNT9B, WNT16, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT7A, WNT10B, WNT1, WNT8A |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines. {ECO:0000269|PubMed:10944466, ECO:0000269|PubMed:8761309}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:26902720}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |