Gene Information
Gene NameZNF377
OrganismHomo sapiens (Human)
Gene Length485
Protein NamesPalmitoyltransferase ZDHHC1 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 1) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8WTX9
Gene CardZDHHC1
Uniprot IDQ8WTX9
PfamPF01529
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed with significant expression in heart, brain, placenta, lung, liver, kidney, testis, thymus and small intestine (PubMed:16647879). Expressed at lower levels in adult pancreas and lung (PubMed:10395086). {ECO:0000269|PubMed:10395086, ECO:0000269|PubMed:16647879}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34229857 
Subcellular location [CC]Endosome membrane {ECO:0000250|UniProtKB:Q8R0N9};
Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16647879, ECO:0000269|PubMed:25299331};
Multi-pass membrane protein {ECO:0000255}. Golgi apparatus {ECO:0000269|PubMed:25299331}.
Mouse PG classificationNA
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