Gene Information
Gene NameACTR5
OrganismHomo sapiens (Human)
Gene Length607
Protein NamesActin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000101442 )
Evolutionary StageEukaryota
AlphaFoldDBQ9H9F9
Gene CardACTR5
Uniprot IDQ9H9F9
PfamPF00022
In ASDno
Allosteric Predictionno (-0.941394734)
Ortholog in AnimalsAlpaca_ ACTR5 ( ortholog_one2one )
Dog_ ACTR5 ( ortholog_one2one )
GuineaPig_ ACTR5 ( ortholog_one2one )
Macaque_ ACTR5 ( ortholog_one2one )
Mouse_ Actr5 ( ortholog_one2one )
Pig_ ACTR5 ( ortholog_one2one )
Rat_ Actr5 ( ortholog_one2one )
Rabbit_ ACTR5 ( ortholog_one2one )
OhnologsNA
ParalogsACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.111363(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6HTS  (EM  4.80A 
DBSNP rs17853829  rs35805905  rs2245231  rs3752289 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:18026119, ECO:0000269|PubMed:18163988, ECO:0000269|PubMed:19014934}. Cytoplasm {ECO:0000269|PubMed:19014934}. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli;
excluded from chromosomes as mitosis progresses (PubMed:18163988).
Mouse PG classificationNA
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