| Gene Information | |
|---|---|
| Gene Name | RHOBTB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000008853 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BYZ6 |
| Gene Card | RHOBTB2 |
| Uniprot ID | Q9BYZ6 |
| Pfam | PF00651; PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.429702367) |
| Ortholog in Animals | Alpaca_ RHOBTB2 ( ortholog_one2one ) Dog_ RHOBTB2 ( ortholog_one2one ) GuineaPig_ RHOBTB2 ( ortholog_one2one ) Macaque_ RHOBTB2 ( ortholog_one2one ) Mouse_ Rhobtb2 ( ortholog_one2one ) Pig_ RHOBTB2 ( ortholog_one2one ) Rat_ Rhobtb2 ( ortholog_one2one ) Rabbit_ RHOBTB2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RND2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain. {ECO:0000269|PubMed:12426103}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1554504656 rs1554504663 rs1563292586 rs1554504678 rs1554504684 rs1554504681 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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