| Gene Information | |
|---|---|
| Gene Name | FKBP14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | Peptidyl-prolyl cis-trans isomerase FKBP14 (PPIase FKBP14) (EC 5.2.1.8) (22 kDa FK506-binding protein) (22 kDa FKBP) (FKBP-22) (FK506-binding protein 14) (FKBP-14) (Rotamase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000106080 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NWM8 |
| Gene Card | FKBP14 |
| Uniprot ID | Q9NWM8 |
| Pfam | PF13499; PF00254 |
| In ASD | no |
| Allosteric Prediction | no (-0.546044234) |
| Ortholog in Animals | Alpaca_ FKBP14 ( ortholog_one2one ) GuineaPig_ FKBP14 ( ortholog_one2one ) Macaque_ FKBP14 ( ortholog_one2one ) Mouse_ Fkbp14 ( ortholog_one2one ) Pig_ FKBP14 ( ortholog_one2one ) Rat_ Fkbp14 ( ortholog_one2one ) Rabbit_ FKBP14 ( ortholog_one2one ) |
| Ohnologs | FKBP7 |
| Paralogs | FKBP11, FKBP3, TTC9, FKBP10, FKBP1A, FKBP1C, FKBP1B, FKBP7, FKBP2, FKBP8, TTC9B, TTC9C, FKBPL, FKBP5, FKBP4, FKBP15, FKBP9, FKBP6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DIP (X-ray 1.82A ) 4MSP (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:22265013}. |
| Mouse PG classification | NA |
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