| Gene Information | |
|---|---|
| Gene Name | TAB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 712 |
| Protein Names | TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000157625 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N5C8 |
| Gene Card | TAB3 |
| Uniprot ID | Q8N5C8 |
| Pfam | PF02845 |
| In ASD | no |
| Allosteric Prediction | no (-0.15663922) |
| Ortholog in Animals | Alpaca_ TAB3 ( ortholog_one2one ) Dog_ TAB3 ( ortholog_one2one ) GuineaPig_ TAB3 ( ortholog_one2one ) Macaque_ TAB3 ( ortholog_one2one ) Mouse_ Tab3 ( ortholog_one2one ) Pig_ TAB3 ( ortholog_one2one ) Rat_ Tab3 ( ortholog_one2one ) Rabbit_ TAB3 ( ortholog_one2one ) |
| Ohnologs | TAB2 |
| Paralogs | TAB2, BTF3L4, BTF3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Constitutively overexpressed in certain tumor tissues. {ECO:0000269|PubMed:14670075}.; [Isoform 1]: Major transcript. {ECO:0000269|PubMed:14766965}.; [Isoform 2]: Minor transcript. {ECO:0000269|PubMed:14766965}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs5927629 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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