| Gene Information | |
|---|---|
| Gene Name | MTUS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1369 |
| Protein Names | Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000132938 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5JR59 |
| Gene Card | MTUS2 |
| Uniprot ID | Q5JR59 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.137892916) |
| Ortholog in Animals | Alpaca_ MTUS2 ( ortholog_one2one ) Dog_ MTUS2 ( ortholog_one2one ) Macaque_ MTUS2 ( ortholog_one2one ) Mouse_ Mtus2 ( ortholog_one2one ) Pig_ MTUS2 ( ortholog_one2one ) Rat_ Mtus2 ( ortholog_one2one ) |
| Ohnologs | MTUS1 |
| Paralogs | CCDC69, MTUS1 |
| Tissue | heart, pancreas |
| Tissue Specificity | Detected in embryonic stem cells differentiating to cardiomyocytes. {ECO:0000269|PubMed:19806667}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.032468(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12874207 rs17073511 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19543227}. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules. |
| Mouse PG classification | NA |
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