| Gene Information | |
|---|---|
| Gene Name | ZNF225 |
| Organism | Homo sapiens (Human) |
| Gene Length | 543 |
| Protein Names | Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000256294 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P18146 |
| Gene Card | EGR1 |
| Uniprot ID | P18146 |
| Pfam | PF11914; PF11928; PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.344192237) |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | ZNF45, ZNF268, ZNF775, ZNF140, ZNF544, ZNF841, ZNF7, ZNF571, ZNF28, GLI4, ZNF732, ZNF595, ZNF718, ZNF493, ZNF117, ZNF141, ZNF607, ZNF484, ZFP3, ZNF790, ZNF540, ZNF286A, ZNF672, ZNF629, ZNF605, ZNF836, ZNF483, ZNF71, ZNF713, MZF1, ZNF460, ZNF517, ZNF585A, ZNF585B, ZNF157, ZNF16, ZNF621, ZNF354B, ZNF615, ZNF471, ZNF677, ZNF502, ZSCAN10, ZNF490, ZNF658, ZNF568, ZNF624, ZNF432, ZNF30, ZNF623, ZNF260, ZNF93, ZNF138, ZNF676, ZNF735, ZNF722, ZNF254, ZNF492, ZNF726, ZNF679, ZNF90, ZNF708, ZNF716, ZNF714, ZNF728, ZNF486, ZNF506, ZNF300, ZNF132, ZIM2, ZNF696, ZNF317, ZNF616, ZFP14, ZNF275, ZNF32, ZNF534, ZFP1, ZNF780A, ZNF182, ZNF234, ZNF782, ZFP28, ZIM3, ZKSCAN5, ZNF415, ZNF573, ZFP2, ZNF189, ZNF519, ZNF195, ZNF429, ZFP30, ZNF699, ZNF630, ZNF829, ZNF383, ZNF43, ZNF655, ZNF543, ZNF227, ZNF345, ZNF354A, ZNF37A, ZNF454, ZNF780B, ZNF267, ZNF814, ZNF2, ZNF226, ZNF546, ZNF331, ZNF283, ZNF628, ZNF565, ZNF879, ZNF74, ZNF311, ZNF501, ZNF3, ZKSCAN8P1, ZNF135, ZNF391, ZNF510, ZNF470, ZNF606, ZNF239, ZNF23, ZNF320, ZFP82, ZNF235, ZNF146, ZNF251, ZNF322, ZNF514, ZNF461, ZNF600, ZNF611, ZNF26, ZNF121, ZNF33A, ZNF33B, ZNF334, ZNF250, ZNF197, ZNF577, ZNF436, ZNF835, ZNF112, ZNF229, ZNF81, ZNF789, ZNF724, ZNF695, ZNF681, ZNF682, ZNF727, ZNF678, ZNF736, ZNF738, ZNF85, ZNF175, ZNF354C, ZNF41, ZNF717, ZNF528, ZNF880, ZNF83, RBAK, ZNF12, ZNF284, ZNF224, ZNF221 |
| Tissue | NA |
| Tissue Specificity | Detected in neutrophils (at protein level). {ECO:0000269|PubMed:20363028}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4R2A (X-ray 1.59A ) 4R2C (X-ray 1.89A ) 4R2D (X-ray 2.09A ) 4X9J (X-ray 1.41A ) 5N14 (NMR - ) |
| DBSNP | rs13181973 rs28365166 rs28365164 rs28365165 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20363028}. Cytoplasm {ECO:0000269|PubMed:20363028}. |
| Mouse PG classification | NA |
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