| Gene Information | |
|---|---|
| Gene Name | PTGIR |
| Organism | Homo sapiens (Human) |
| Gene Length | 386 |
| Protein Names | Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor) |
| Target Name | prostacyclin receptor |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000160013 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P43119 |
| Gene Card | PTGIR |
| Uniprot ID | P43119 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.054307857) |
| Ortholog in Animals | Alpaca_ PTGIR ( ortholog_one2one ) GuineaPig_ PTGIR ( ortholog_one2one ) Macaque_ PTGIR ( ortholog_one2one ) Mouse_ Ptgir ( ortholog_one2one ) Pig_ PTGIR ( ortholog_one2one ) Rat_ Ptgir ( ortholog_one2one ) Rabbit_ PTGIR ( ortholog_one2one ) |
| Ohnologs | PTGER2, PTGDR |
| Paralogs | PTGER2, PTGDR, PTGER4, PTGER3, PTGFR, TBXA2R, PTGER1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2229127 rs28590598 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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