| Gene Information | |
|---|---|
| Gene Name | DDIT4L |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | DNA damage-inducible transcript 4-like protein (HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000145358 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96D03 |
| Gene Card | DDIT4L |
| Uniprot ID | Q96D03 |
| Pfam | PF07809 |
| In ASD | no |
| Allosteric Prediction | no (-1.190137965) |
| Ortholog in Animals | Alpaca_ DDIT4L ( ortholog_one2one ) Dog_ DDIT4L ( ortholog_one2one ) GuineaPig_ DDIT4L ( ortholog_one2one ) Macaque_ DDIT4L ( ortholog_one2one ) Mouse_ Ddit4l ( ortholog_one2one ) Pig_ DDIT4L ( ortholog_one2one ) Rat_ Ddit4l ( ortholog_one2one ) Rabbit_ DDIT4L ( ortholog_one2one ) |
| Ohnologs | DDIT4 |
| Paralogs | DDIT4 |
| Tissue | skeletal.muscle |
| Tissue Specificity | Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. {ECO:0000269|PubMed:15308555}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11553154 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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