| Gene Information | |
|---|---|
| Gene Name | MT-ND4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 459 |
| Protein Names | NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4) |
| Target Name | nadh-ubiquinone oxidoreductase chain 4 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000198886 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P03905 |
| Gene Card | MT-ND4 |
| Uniprot ID | P03905 |
| Pfam | PF01059; PF00361 |
| In ASD | no |
| Allosteric Prediction | no (-0.399938204) |
| Ortholog in Animals | Alpaca_ ND4 ( ortholog_one2one ) Alpaca_ MT-ND4 ( ortholog_one2one ) GuineaPig_ ND4 ( ortholog_one2one ) Macaque_ ND4 ( ortholog_one2one ) Mouse_ mt-Nd4 ( ortholog_one2one ) Pig_ ND4 ( ortholog_one2one ) Rat_ Mt-nd4 ( ortholog_one2one ) Rabbit_ ND4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MT-ND2, MT-ND5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.375913(Chimpanzee);0.336179(Mouse);0.643390(Rat);0.271659(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs199476113 rs1603223136 rs200873900 rs199476112 rs879136236 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03910}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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