| Gene Information | |
|---|---|
| Gene Name | PELI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000197329 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96FA3 |
| Gene Card | PELI1 |
| Uniprot ID | Q96FA3 |
| Pfam | PF04710 |
| In ASD | no |
| Allosteric Prediction | no (-0.319275078) |
| Ortholog in Animals | Alpaca_ PELI1 ( ortholog_one2one ) Dog_ PELI1 ( ortholog_one2one ) GuineaPig_ PELI1 ( ortholog_one2one ) Macaque_ PELI1 ( ortholog_one2one ) Mouse_ Peli1 ( ortholog_one2one ) Pig_ PELI1 ( ortholog_one2one ) Rat_ Peli1 ( ortholog_one2many ) Rabbit_ PELI1 ( ortholog_one2one ) |
| Ohnologs | PELI2, PELI3 |
| Paralogs | PELI3, PELI2 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in normal skin but decreased in keratinocytes from toxic epidermal necrolysis (TEN) patients (at protein level). {ECO:0000269|PubMed:29883609}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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