| Gene Information | |
|---|---|
| Gene Name | EEA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1411 |
| Protein Names | Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) |
| Target Name | early endosome antigen 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000102189 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q15075 |
| Gene Card | EEA1 |
| Uniprot ID | Q15075 |
| Pfam | PF01363 |
| In ASD | no |
| Allosteric Prediction | no (-0.210381779) |
| Ortholog in Animals | Alpaca_ EEA1 ( ortholog_one2one ) Dog_ EEA1 ( ortholog_one2one ) GuineaPig_ EEA1 ( ortholog_one2one ) Macaque_ EEA1 ( ortholog_one2one ) Mouse_ Eea1 ( ortholog_one2one ) Pig_ EEA1 ( ortholog_one2one ) Rat_ Eea1 ( ortholog_one2one ) Rabbit_ EEA1 ( ortholog_one2one ) |
| Ohnologs | CENPF, GOLGA4, GOLGB1 |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1HYI (NMR - ) 1HYJ (NMR - ) 1JOC (X-ray 2.20A ) 3MJH (X-ray 2.03A ) |
| DBSNP | rs10745623 |
| Subcellular location [CC] | Cytoplasm. Early endosome membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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