Gene Information | |
---|---|
Gene Name | PCYT1A |
Organism | Homo sapiens (Human) |
Gene Length | 367 |
Protein Names | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) |
Target Name | choline-phosphate cytidylyltransferase a |
Target Type | NA |
Gene Age | 645 ( ENSG00000161217 ) |
Evolutionary Stage | Eukaryota |
AlphaFoldDB | P49585 |
Gene Card | PCYT1A |
Uniprot ID | P49585 |
Pfam | PF01467 |
In ASD | yes |
Allosteric Prediction | yes (0.692093077) |
Ortholog in Animals | Alpaca_ PCYT1A ( ortholog_one2one ) Dog_ PCYT1A ( ortholog_one2one ) GuineaPig_ PCYT1A ( ortholog_one2one ) Macaque_ PCYT1A ( ortholog_one2one ) Mouse_ Pcyt1a ( ortholog_one2one ) Pig_ PCYT1A ( ortholog_one2one ) Rat_ Pcyt1a ( ortholog_one2one ) Rabbit_ PCYT1A ( ortholog_one2one ) |
Ohnologs | PCYT1B |
Paralogs | PCYT1B, PCYT2 |
Tissue | NA |
Tissue Specificity | Brain, placenta, liver, fetal and adult lung. {ECO:0000269|PubMed:10480912}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | NA |
DBSNP | rs587777191 rs587777189 rs587777194 rs587777190 rs587777195 rs540053239 |
Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum {ECO:0000269|PubMed:10480912}. Nucleus {ECO:0000269|PubMed:10480912}. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836}. |
Mouse PG classification | LPG |
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