| Gene Information | |
|---|---|
| Gene Name | ACTL9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Actin-like protein 9 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000181786 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TC94 |
| Gene Card | ACTL9 |
| Uniprot ID | Q8TC94 |
| Pfam | PF00022 |
| In ASD | no |
| Allosteric Prediction | no (-1.214402765) |
| Ortholog in Animals | Alpaca_ ACTL9 ( ortholog_one2one ) Dog_ ACTL9 ( ortholog_one2one ) GuineaPig_ ACTL9 ( ortholog_one2one ) Macaque_ ACTL9 ( ortholog_one2one ) Mouse_ Actl9 ( ortholog_one2one ) Pig_ ACTL9 ( ortholog_one2one ) Rat_ Actl9 ( ortholog_one2many ) Rat_ Actl9b ( ortholog_one2many ) Rabbit_ ACTL9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTG2, ACTA2, ACTR10 |
| Tissue | testis |
| Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:33626338}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2340550 rs10410943 rs4804079 rs782721280 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:33626338}. Cytoplasm, cytoskeleton, perinuclear theca {ECO:0000269|PubMed:33626338}. Note=Localizes predominantly in the equatorial segment of the sperm head and neck regions, with some localization in the acrosomal segment of the head. Colocalizes in the acrosomal and equatorial segments of sperm with ACTL7A. Colocalizes with PLCZ1 in the equatorial segment of the head of capacitated sperm. {ECO:0000269|PubMed:33626338}. |
| Mouse PG classification | NA |
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