| Gene Information | |
|---|---|
| Gene Name | ZFYVE23 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1462 |
| Protein Names | FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZNL6 |
| Gene Card | FGD5 |
| Uniprot ID | Q6ZNL6 |
| Pfam | PF01363; PF00169; PF00621 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in endothelial cells (at protein level). {ECO:0000269|PubMed:22328776}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MPX (X-ray 2.80A ) |
| DBSNP | rs7636593 rs17038795 rs2307092 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22328776}. Cell projection, ruffle membrane {ECO:0000269|PubMed:22328776}. Endoplasmic reticulum {ECO:0000269|PubMed:22328776}. Golgi apparatus {ECO:0000269|PubMed:22328776}. Early endosome {ECO:0000269|PubMed:22328776}. Note=In peripheral membrane ruffles, colocolizes with F-actin. In confluent HUVECs, detected at cell-cell-contact sites where it colocalizes with vascular endothelial cadherin/CDH5. |
| Mouse PG classification | NA |
| click here to return to the previous page | |