| Gene Information | |
|---|---|
| Gene Name | ZFR |
| Organism | Homo sapiens (Human) |
| Gene Length | 1074 |
| Protein Names | Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000056097 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96KR1 |
| Gene Card | ZFR |
| Uniprot ID | Q96KR1 |
| Pfam | PF07528 |
| In ASD | no |
| Allosteric Prediction | no (-0.834678692) |
| Ortholog in Animals | Alpaca_ ZFR ( ortholog_one2one ) GuineaPig_ ZFR ( ortholog_one2one ) Macaque_ ZFR ( ortholog_one2one ) Mouse_ Zfr ( ortholog_one2one ) Pig_ ZFR ( ortholog_one2one ) Rat_ Zfr ( ortholog_one2one ) Rabbit_ ZFR ( ortholog_one2one ) |
| Ohnologs | ZFR2, STRBP |
| Paralogs | TARBP2, ADAT1, ADARB2, PRKRA, ILF3, STRBP, ADAD1, ADARB1, STAU2, ILF2, ZFR2, STAU1, ADAR, ADAD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney. {ECO:0000269|PubMed:11574164}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587777203 rs4867440 rs1051489 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000250}. Chromosome {ECO:0000250}. Note=Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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