| Gene Information | |
|---|---|
| Gene Name | GPX6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 187 |
| Protein Names | Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) |
| Target Name | glutathione peroxidase 6 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000198704 ) 3 ( ENSG00000281185 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96SL4 |
| Gene Card | GPX7 |
| Uniprot ID | Q96SL4 |
| Pfam | PF00255 |
| In ASD | no |
| Allosteric Prediction | no (-0.695000031) |
| Ortholog in Animals | Alpaca_ GPX6 ( ortholog_one2one ) Dog_ GPX6 ( ortholog_one2one ) Macaque_ GPX6 ( ortholog_one2one ) Mouse_ Gpx6 ( ortholog_one2one ) Pig_ GPX6 ( ortholog_one2one ) Rat_ Gpx6 ( ortholog_one2one ) Rabbit_ GPX6 ( ortholog_one2one ) |
| Ohnologs | GPX1P1, GPX3 |
| Paralogs | GPX3, GPX4, GPX7, GPX8, GPX1, GPX5, GPX2 |
| Tissue | NA |
| Tissue Specificity | Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids. {ECO:0000269|PubMed:22157330}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2P31 (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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