| Gene Information | |
|---|---|
| Gene Name | HAS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 578 |
| Protein Names | Hyaluronan synthase 1 (EC 2.4.1.212) (Hyaluronate synthase 1) (Hyaluronic acid synthase 1) (HA synthase 1) (HuHAS1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105509 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q92839 |
| Gene Card | HAS1 |
| Uniprot ID | Q92839 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.458969336) |
| Ortholog in Animals | Alpaca_ HAS1 ( ortholog_one2one ) Dog_ HAS1 ( ortholog_one2one ) GuineaPig_ HAS1 ( ortholog_one2one ) Macaque_ HAS1 ( ortholog_one2one ) Mouse_ Has1 ( ortholog_one2one ) Pig_ HAS1 ( ortholog_one2one ) Rat_ Has1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HAS2, HAS3 |
| Tissue | greater.omentum |
| Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. {ECO:0000269|PubMed:8651928}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7248778 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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