| Gene Information | |
|---|---|
| Gene Name | TAS2R43 |
| Organism | Homo sapiens (Human) |
| Gene Length | 309 |
| Protein Names | Taste receptor type 2 member 43 (T2R43) (Taste receptor type 2 member 52) (T2R52) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000255374 ) 3 ( ENSG00000262612 ) 3 ( ENSG00000282537 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P59537 |
| Gene Card | TAS2R43 |
| Uniprot ID | P59537 |
| Pfam | PF05296 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000091664) |
| Ortholog in Animals | Alpaca_ TAS2R43 ( ortholog_one2one ) Dog_ CAFA-T2R43 ( ortholog_many2many ) Mouse_ Tas2r120 ( ortholog_many2many ) Mouse_ Tas2r136 ( ortholog_many2many ) Rat_ Tas2r136 ( ortholog_many2many ) Rat_ Tas2r120 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | TAS2R31, TAS2R30, TAS2R46, TAS2R50, TAS2R20, TAS2R19, TAS2R14, TAS2R13, TAS2R42, TAS2R10, TAS2R9, TAS2R8, TAS2R7, TAS2R3, TAS2R5, TAS2R38, TAS2R1, TAS2R41, TAS2R60, TAS2R16, TAS2R4, TAS2R39, TAS2R40 |
| Tissue | NA |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in airway epithelia. {ECO:0000269|PubMed:19628819}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:19628819}; Multi-pass membrane protein {ECO:0000269|PubMed:19628819}. Cell projection, cilium membrane {ECO:0000269|PubMed:19628819}. Note=In airway epithelial cells, localizes to motile cilia. |
| Mouse PG classification | NA |
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