| Gene Information | |
|---|---|
| Gene Name | ZDHHC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Acyltransferase ZDHHC3) (EC 2.3.1.-) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000163812 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NYG2 |
| Gene Card | ZDHHC3 |
| Uniprot ID | Q9NYG2 |
| Pfam | PF01529 |
| In ASD | no |
| Allosteric Prediction | no (-0.891305114) |
| Ortholog in Animals | Alpaca_ ZDHHC3 ( ortholog_one2one ) Dog_ ZDHHC3 ( ortholog_one2one ) GuineaPig_ ZDHHC3 ( ortholog_one2one ) Macaque_ ZDHHC3 ( ortholog_one2one ) Mouse_ Zdhhc3 ( ortholog_one2one ) Pig_ ZDHHC3 ( ortholog_one2one ) |
| Ohnologs | ZDHHC7 |
| Paralogs | ZDHHC6, ZDHHC21, ZDHHC1, ZDHHC7, ZDHHC20, ZDHHC2, ZDHHC12, ZDHHC18, ZDHHC23, ZDHHC4, ZDHHC9, ZDHHC22, ZDHHC11, ZDHHC11B, ZDHHC15, ZDHHC14, ZDHHC19 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with significant expression in heart, lung, liver, skeletal muscle, kidney, testis, thymus, small intestine and leukocyte. {ECO:0000269|PubMed:16647879}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:16647879, ECO:0000269|PubMed:19001095, ECO:0000269|PubMed:21926431, ECO:0000269|PubMed:26535572}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to the Golgi cis cisterna. {ECO:0000250|UniProtKB:Q8R173}. |
| Mouse PG classification | NA |
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