| Gene Information | |
|---|---|
| Gene Name | ZDHHC22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 263 |
| Protein Names | Palmitoyltransferase ZDHHC22 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 22) (DHHC-22) (zDHHC22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000177108 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N966 |
| Gene Card | ZDHHC22 |
| Uniprot ID | Q8N966 |
| Pfam | PF01529 |
| In ASD | no |
| Allosteric Prediction | no (-1.361736123) |
| Ortholog in Animals | Alpaca_ ZDHHC22 ( ortholog_one2one ) Dog_ ZDHHC22 ( ortholog_one2one ) GuineaPig_ ZDHHC22 ( ortholog_one2one ) Macaque_ ZDHHC22 ( ortholog_one2one ) Mouse_ Zdhhc22 ( ortholog_one2one ) Pig_ ZDHHC22 ( ortholog_one2one ) Rat_ Zdhhc22 ( ortholog_one2one ) Rabbit_ ZDHHC22 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZDHHC6, ZDHHC21, ZDHHC1, ZDHHC7, ZDHHC20, ZDHHC2, ZDHHC12, ZDHHC18, ZDHHC23, ZDHHC4, ZDHHC9, ZDHHC11, ZDHHC11B, ZDHHC3, ZDHHC15, ZDHHC14, ZDHHC19 |
| Tissue | brain, cerebral.cortex, amygdala, cerebellar.hemisphere, cerebellum, hippocampus, hypothalamus, substantia.nigra |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16647879}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16647879}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:16647879}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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