| Gene Information | |
|---|---|
| Gene Name | KRTAP10-8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 259 |
| Protein Names | Keratin-associated protein 10-8 (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 86 ( ENSG00000187766 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P60410 |
| Gene Card | KRTAP10-8 |
| Uniprot ID | P60410 |
| Pfam | PF13885; PF05287 |
| In ASD | no |
| Allosteric Prediction | no (-1.096634518) |
| Ortholog in Animals | Alpaca_ KRTAP10-8 ( ortholog_one2one ) Macaque_ KRTAP10-8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KRTAP5-2, KRTAP5-5, KRTAP16-1, KRTAP10-6, KRTAP10-9, KRTAP4-5, KRTAP4-2, KRTAP4-1, KRTAP1-4, KRTAP1-5, KRTAP1-1, KRTAP1-3, KRTAP10-1, KRTAP10-3, KRTAP10-5, KRTAP5-6, KRTAP5-8, KRTAP2-1, KRTAP2-3, KRTAP2-2, KRTAP2-4, KRTAP4-6, KRTAP4-7, KRTAP4-12, KRTAP9-2, KRTAP9-6, KRTAP9-3, KRTAP9-9, KRTAP9-8, KRTAP9-7, KRTAP9-4, KRTAP4-3, KRTAP10-11, KRTAP10-4, KRTAP4-11, KRTAP4-8, KRTAP4-9, KRTAP4-16, KRTAP4-4, KRTAP10-10, KRTAP10-7, KRTAP12-1, KRTAP12-2, KRTAP12-3, KRTAP9-1, KRTAP10-2, KRTAP10-12 |
| Tissue | NA |
| Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs411254 rs763238933 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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