| Gene Information | |
|---|---|
| Gene Name | ZCCHC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000168228 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H5U6 |
| Gene Card | ZCCHC4 |
| Uniprot ID | Q9H5U6 |
| Pfam | PF10237; PF06839 |
| In ASD | no |
| Allosteric Prediction | no (-1.623164518) |
| Ortholog in Animals | Alpaca_ ZCCHC4 ( ortholog_one2one ) Dog_ ZCCHC4 ( ortholog_one2one ) GuineaPig_ ZCCHC4 ( ortholog_one2one ) Mouse_ Zcchc4 ( ortholog_one2one ) Pig_ ZCCHC4 ( ortholog_one2one ) Rat_ Zcchc4 ( ortholog_one2one ) Rabbit_ ZCCHC4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6UCA (X-ray 3.10A ) |
| DBSNP | rs3752873 rs315675 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:30531910, ECO:0000269|PubMed:31799605}. Cytoplasm {ECO:0000269|PubMed:30531910}. Note=Accumulates in the nucleolus, where ribosome biogenesis takes place. {ECO:0000269|PubMed:30531910}. |
| Mouse PG classification | NA |
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