| Gene Information | |
|---|---|
| Gene Name | ZBU1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1009 |
| Protein Names | Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14527 |
| Gene Card | HLTF |
| Uniprot ID | Q14527 |
| Pfam | PF00271; PF08797; PF00176 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. {ECO:0000269|PubMed:8672239, ECO:0000269|PubMed:9126292}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MZN (NMR - ) 4HRE (X-ray 2.79A ) 4HRH (X-ray 3.00A ) 4S0N (X-ray 1.50A ) 4XZF (X-ray 1.38A ) 4XZG (X-ray 2.40A ) 5BNH (X-ray 1.70A ) 5K5F (NMR - ) 6KCS (X-ray 2.10A ) |
| DBSNP | rs2305868 rs2228257 rs2229361 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:8672239}. Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Nuclear localization is stimulated by progesterone. {ECO:0000250}. |
| Mouse PG classification | NA |
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