| Gene Information | |
|---|---|
| Gene Name | ZBTB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 584 |
| Protein Names | Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95365 |
| Gene Card | ZBTB7A |
| Uniprot ID | O95365 |
| Pfam | PF00651; PF00096 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (PubMed:9927193). In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level) (PubMed:15662416). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level) (PubMed:15662416). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level) (PubMed:15662416). Expressed in adipose tissues (PubMed:14701838). {ECO:0000269|PubMed:14701838, ECO:0000269|PubMed:15662416, ECO:0000269|PubMed:9927193}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2IF5 (X-ray 2.00A ) 2NN2 (X-ray 2.10A ) 7EYI (X-ray 2.40A ) 7N5S (X-ray 2.86A ) 7N5T (X-ray 2.90A ) 7N5U (X-ray 2.86A ) 7N5V (X-ray 3.08A ) 7N5W (X-ray 2.24A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17595526, ECO:0000269|PubMed:24514149}. Note=Recruited to double-strand break sites of damaged DNA. {ECO:0000250|UniProtKB:O88939}. |
| Mouse PG classification | NA |
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