| Gene Information | |
|---|---|
| Gene Name | ZBTB33 |
| Organism | Homo sapiens (Human) |
| Gene Length | 672 |
| Protein Names | Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000177485 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q86T24 |
| Gene Card | ZBTB33 |
| Uniprot ID | Q86T24 |
| Pfam | PF00651 |
| In ASD | no |
| Allosteric Prediction | no (-0.661920523) |
| Ortholog in Animals | Alpaca_ ZBTB33 ( ortholog_one2one ) Dog_ ZBTB33 ( ortholog_one2one ) GuineaPig_ ZBTB33 ( ortholog_one2one ) Macaque_ ZBTB33 ( ortholog_one2one ) Mouse_ Zbtb33 ( ortholog_one2one ) Pig_ ZBTB33 ( ortholog_one2one ) Rat_ Zbtb33 ( ortholog_one2one ) Rabbit_ ZBTB33 ( ortholog_one2one ) |
| Ohnologs | ZBTB38 |
| Paralogs | FEZF1, PRDM12, ZNF280A, ZBTB21, ZNF280C, NACC2, ZNF580, ZBTB26, NACC1, ZNF683, ZBTB7B, GFI1, PRDM13, ZNF280B, ZBTB6, ZBTB14, GFI1B, BCL6, ZBTB49, BCL6B, ZBTB3, ZNF581, FEZF2, ZNF280D, ZBTB46, ZNF524, ZBTB12, ZBTB25 |
| Tissue | NA |
| Tissue Specificity | Expressed in vascular endothelium. {ECO:0000269|PubMed:14699141}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LT7 (NMR - ) 3FKC (X-ray 1.70A ) 3M4T (X-ray 2.05A ) 3M8V (X-ray 2.70A ) 4F6M (X-ray 2.40A ) 4F6N (X-ray 2.80A ) 5VMU (X-ray 2.35A ) 5VMV (X-ray 2.31A ) 5VMW (X-ray 2.40A ) 5VMX (X-ray 2.05A ) 5VMY (X-ray 2.00A ) 5VMZ (X-ray 2.32A ) 6DF5 (X-ray 1.82A ) 6DF8 (X-ray 2.54A ) 6DF9 (X-ray 2.32A ) 6DFA (X-ray 1.91A ) 6DFB (X-ray 1.66A ) 6DFC (X-ray 1.85A ) 6V8U (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15781635, ECO:0000269|PubMed:16354688}. Cytoplasm {ECO:0000269|PubMed:15781635}. Note=Also cytoplasmic in cells grown at high densities. |
| Mouse PG classification | NA |
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