| Gene Information | |
|---|---|
| Gene Name | ZASP |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75112 |
| Gene Card | LDB3 |
| Uniprot ID | O75112 |
| Pfam | PF15936; PF00412; PF00595 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta. {ECO:0000269|PubMed:10427098}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RGW (NMR - ) 4YDP (X-ray 1.40A ) |
| DBSNP | rs3740343 rs45592139 rs45487699 rs121908337 rs121908336 rs45618633 rs45514002 rs121908338 rs121908333 rs121908334 rs121908338 rs121908333 rs121908334 rs121908335 rs121908335 rs121908333 rs121908334 rs121908335 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:10427098}. Cell projection, pseudopodium {ECO:0000269|PubMed:10427098}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10427098}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:10427098}. Note=Localized to the cytoplasm around nuclei and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2 at the Z-lines. |
| Mouse PG classification | NA |
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